680975-913 - AdvanceBio Glycan Map 4.6x250, 2.7um. Speed—Obtain glycan maps in less than 10 minutes; High-resolution—Characterize both labeled and unlabeled glycans; identify any glycosylation changes that occur due to process variables; Flexibility—Choose from: 2.7 µm superficially porous particles for high resolution with less backpressure—compatible with all LC instruments There are three stages used in glycan analysis that are common to all analytical approaches—sample preparation, separation/detection, and analysis—and Agilent has taken significant steps to advance all three. At Agilent Lance assists customers with method development, column recommendations, and troubleshooting challenging biomolecule separations. Agilent Technologies 7820A GC System 5975 Series Gas Mass Selective Detector (GC-MS) The GC-MS system is equipped with Agilent Technologies 7820A gas chromatography system with Rtx-5ms capillary column (30m x 0.25mm x 0.25µm) and coupled to 5975 mass selective detector. Glycan Standards Structures Technical Flyer, Critical Quality Attributes application compendium. Agilent (A) agrees to acquire glycan analysis company ProZyme for an undisclosed amount. “ProZyme is a market leader and innovator in the glycan consumable space. The workflow, illustrated below, involves six major steps: The glycoprotein is denatured to unravel its tertiary structure (sometimes also cleaved into peptides, depending on the protocol being used) and make glycans more accessible. ProZyme, Inc. Now Agilent covers the complete glycan analysis workflow. Agilent / Glycan Analysis; Browse By: Glycan Analysis. “ProZyme is a market leader and innovator in the glycan consumable space. of the Agilent AssayMAP Bravo . Transfer 3 μl of the appropriate matrix solution (either DHB or Super DHB at 10 mg/ml) into a 0.5 ml Eppendorf ® tube. Physical Analysis; Lab Devices ; Cleaning & Disinfection Supplies ... -linked glycan library, 2-AB labeled; Product was successfully added to your shopping cart. Santa Clara, CA 6/28/18—Agilent Technologies has entered into an agreement to purchase ProZyme, a provider of glycan analysis reagents, kits and standards, for an undisclosed amount.“ProZyme is a market leader and innovator in the glycan consumable space. HPLC-based glycan analysis can be categorized by the chosen detection method and the detail in the information sought. Glycan Analysis, Agilent T echnologies . The Agilent AdvanceBio Gly-X (formerly ProZyme) technology is a new generation of N-glycan sample preparation. SEP 10, 2020 9:00 AM PDT C.E. Agilent AdvanceBio Glycan Mapping Columns are designed and manufactured to deliver fast, high resolution, reproducible glycan identification using HILIC chromatography. Pioneer of high-performance cell analysis platforms for life science research. Description. GlykoPrep®-plus Rapid N-Glycan Sample Preparation with 2-AB, configured for automation on the Agilent AssayMAP Bravo Liquid Handling Platform.Contains: GSP-RX Digestion Module GS96-AB Rapid-Reductive-Amination™ 2-AB Labeling Module ; GSP-CU Cleanup Module AM96-NG GlykoPrep®-plus Labware Set; Size: 1 Kit (96-ct) Product Code: GPPNG-AB Tech Info Post-translational modifications to the primary amino acid sequence, including glycosylation, have functional consequences and can impact efficacy and immunogenicity of a biopharmaceutical. Agilent, a global leader in life science, diagnostics, and analytical laboratory technologies, will host the Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis, September 22, 2020, opening at 7:00 AM PDT.. Waters' workflow for released N-glycan sample preparation and analysis is built around the capabilities of the GlycoWorks RapiFluor-MS Kit.Our protocol significantly simplifies sample preparation, allowing deglycosylation, labeling, and sample clean-up to be completed within 30 minutes. The Agilent GlykoPrep (formerly ProZyme) platform streamlines N-glycan sample preparation. 651750-913 - AdvanceBio Glycan Map 2.1x250, 2.7um. Copyright © 1999-2021 John Wiley & Sons, Inc. All rights reserved, Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, By continuing to browse this site, you agree to its use of cookies as described in our, Thermo Fisher introduces new handheld XRF analyzer, Tecan invests in Labforward to further drive lab digitalization, Thermo Fisher launches new analytical subscription service, Agilent acquires molecular diagnostics company, Agilent to Acquire Advanced Analytical Technologies. LEARN MORE. If yes then what are the conditions and buffer systems to be used for such analysis? Read independent reviews on Glycan Standards & Libraries from Agilent Technologies on SelectScience A Novel HILIC Column for High Speed N-linked Glycan Analysis, Agilent Technologies Application Note, publication number 5991-4886EN, 2014. The Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis will feature seven speakers such as Christopher Colangelo, PhD, MBA, Biopharma Business Development Leader, Rebecca Glaskin, Application Scientist, Agilent Technologies, David Wong, PhD, Sr. Push your Glycoprotein analysis to new levels of performance. kbusch Aug 14, 2019 2:50 AM Biol. per page. Go to cart Continue N-linked glycan library, 2-AB labeled. “Glycan analysis is essential to the discovery, development, and quality control testing of the ever-growing pipeline of biotherapeutic drug products,” said Padraig McDonnell, vice president and general manager of Agilent’s Chemistries and Supplies Division. [Google Scholar] Ruhaak L.R., Miyamoto S., Lebrilla C.B., 2013. Conclusions • This study highlights the versatility . LEARN MORE. Agilent Technologies A Quaternary LC System, together with fluorescence detection, provides an optimal method for the sensitive and high-resolving analysis of 2-AB derivatised glycans released from mAbs and other glycoproteins. (5)Department of Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway. Agilent Technologies, a global leader in life science, diagnostics, and analytical laboratory technologies, to host Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis, on September 22, 2020. Lebrilla’s laboratory has several such systems, including basic HPLC, UPLC and a nanoLC—an Agilent quadrupole-TOF with a microfluidic HPLC-Chip interface on the front end. 347, 125–143. Agilent, a global leader in life science, diagnostics, and analytical laboratory technologies, will host the Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis, September 22, 2020, opening at 7:00 AM PDT.. Agilent Technologies has entered into a definitive agreement to acquire privately-held ProZyme, Inc., a leading provider of glycan analysis reagents, kits and standards.This acquisition will expand Agilent’s portfolio of biopharma consumables in the fast-growing glycan market. Simple and integrated LIMS and ELN laboratory software solutions. Stay up to date with analytical science product and industry news. “Our glycobiology and glycoanalysis expertise together with Agilent’s market-leading position in LC and LC/MS will allow us to provide our biopharma customers with complete solutions they need to accelerate their research.” ProZyme is headquartered in Hayward, California, US, and employs 47 people. 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